New Long-Term Study Shows Vaping Doesn’t Damage Lung Function


The 24-Month study observed “no serious adverse events” related to e-cigarette use

A brand new study is being published next month in the Regulatory Toxicology and Pharmacology Journal. The lead researcher was Tanvir Walele, Director of Scientific Affairs for Fontem Ventures, a division of Imperial Brands LLC, the makers of the Blu e-cigarette. Walele and his team were based out of the Research and Development Center in Liverpool, UK.

They set out to better understand the effects of vaping long term, and were primarily concerned with lung function, as it’s the most negatively affected system by smoking. The results of their two-year study are nothing short of incredibly encouraging for anyone wondering if making the switch to vaping is safe long term.

The Study

The researchers found 209 otherwise healthy smokers to take part in the study. Each participant was given a vaporizer device called Puritane, which the researchers called “representative of a typical closed system Electronic Vapor Product.” They were instructed to use it as their only vaporizer over the following 24 months. Alternatively, they did not have to agree to stop smoking traditional cigarettes to qualify, as long as they were vaping at least 80% of the time. This is because the researchers wanted to see how vaporizers function in the real world, where many people dual-use at first.

As a baseline before the test, each individual was screened and cleared of any abnormalities in their electrocardiogram test, vital signs, and spirometry. Some participants reported minor side effects at first, including a headache (28.7%), sore throat (19.6%), and cough (16.7%). But these issues mostly resolved themselves after only a few weeks on the product. After two months, the reported nicotine withdrawal symptoms dropped off significantly. But what’s much more encouraging is around the same time the number of traditional cigarettes smoked started to decrease among all participants, with many ultimately quitting.

After the 24-month study was complete, almost half of the original 209 participants had completed the full trial. Among those “completers” there were no signs of clinically significant adverse changes in biomarkers of hematology or lipid metabolism. The researchers noted, “the frequency of adverse events steadily decreased throughout the study.” Coupled with the lack of observed damage to lung function, the decreasing likelihood of AEs shows that vaping has a legitimate case for being a long-term smoking cessation tool.

Vaping As A Smoking Cessation Tool

While this study suggests that vaping is a useful harm reduction tool, other recent studies have begun to prove that e-cigarettes are a valuable smoking cessation tool as well. Late last year, researchers at the University of Louisville set out to understand which smoking cessation methods have the highest likelihood of being successful. Their research indicates that vaping has the best chance to help smokers kick the habit, even handily beating out prescription drugs like Chantix.

Another study from last year found that over half (52%) of daily vapers eventually quit smoking for good. The same survey found that only around 12% of participants who just vaped some days were successful in their quit attempt, showing the importance of committing to the switch. The joint effort by Columbia and Rutgers Universities concluded that e-cigarettes might have a significant role to play in getting and keeping smokers off cigarettes.


It’s worth noting that this research was funded by a vaping company, and therefore could possibly be subject to bias. But to be published in a well known and respected peer-reviewed journal such as Regulatory Toxicology and Pharmacology, the science must make sense and be valid. Furthermore, none of their results are vastly different than what many completely unbiased researchers have reported in recent years.

If you’re willing to look past the potential bias, you’ll find another substantial piece of research that supports the belief that vaping is much safer than smoking. Public Health England, the federal health organization for England, released a report almost three years ago that claimed vaping is at least 95% safer than smoking. Since then many studies have reached a similar understanding of the relative risk of vaping vs. smoking.

But more importantly is that we have more long-term studies finally answering those who worry about the effects of consistently vaping over several years. These types of studies are incredibly critical now. The majority of media coverage of e-cigarettes is still negative, but solid long-term research is all that’s missing to make an ironclad case for vaping.

Have you experienced any adverse events due to switching to vaping? If so, what were they and how long did they persist? Do you think this study is valuable, even being funded by a vaping company? Let us know what you think in the comments.

Dustin has been vaping for almost a decade. He found e-cigarettes in 2008 and quickly became drawn to them as an early adopter. He's been writing reviews ever since and has established himself as a well-versed authority on the subject.

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8 Responses

  1. Asa Saligupta says:

    Hi, I’ve been vaping regularly for over 5 years coming to 6 years now. My health in general is much better than 6 years ago. Now I’m a co-founder of ENDs Cigarette Smoke Thailand (ECST) which is a member of INNCO. I’ve been following your articles and translating then in to Thai (the language use in Thailand). It’s a very bad situation here where some of the top people try all their might to stand against vaping. They use all kind of stupid tactics and the worse is that they are an elite group controlling The Public Health Ministry and ordered other ministries to put ban of vaping. If you want more details please do not hesitate to contact me via this email.
    Sincerely yours,
    Asa “Ace Vaper” Saligupta

  2. Stewart says:

    In my opinion the Government, or any other negative Vaping gang, will never fund a long term study. When they get the same result from it, they would have to shut up and stop demonising Vaping, for the healthier alternative that it is. I have been Vaping for over 5 years and I can honestly say that I feel, and are a lot healthier. It is the best thing I have ever done. I was a smoker for 40 years and tried everything to quit. Patches, willpower, tablets and more only kept me off cigarettes for a short while. Now with Vaping I would not even think about smoking one.

  3. Kit Builder says:

    Let us hope that the UK TPD laws are relaxed after a couple of these reports.

  4. robert cioli says:

    I have been vaping for over 3 years since I have quit cigarettes, I have been able to breathe better, eat better

  5. Clark Newman says:

    I have been vapeing for 6 years and have been off cigs for 2 years 6 months I haven’t had a heart attack for 4 years. The last heart attack came one day after smoking 1 cig within 30 min. . Myself I love vapeing and feel it is much more safer for me.

  6. Betty Greene says:

    I have COPD from smoking. I quit the day I went to a vape shop and got my first device. I’m on 5 ltrs O2 24/7. Any exertion drops my O2 to the 80%. Working with my physical therapist one day, she admonished me against vaping. I put my O2 meter on and vaped. As I did, my O2 level ROSE. She was stunned and I spent an hour answering her questions.

  7. Jacques Ambrose says:

    I’m a newbie in vaping terms, seeing as I only started vaping on 2 Aug 2017, but I have not bought or smoked a tobacco cigarette since. It was hard at first, because my body craved the chemicals mixed with tobacco and nicotine, but it went away within a week or so. I do light up for my wife when she drives, but the cigarettes taste gross. Switching to vaping was the best choice I ever made. I’ve tried Nicorette gum, patches, Twisp oil e-cigs, Quit mouthspray and almost every other gimmick to get off tobacco cigarettes, but nothing worked. Now, 8 months later, my sense of taste and smell has improved, my smoker cough is gone and I feel much better. 30+ years of smoking and vaping got me off with my first little Smok AIO stick. I’m even down on my nicotine, started on 6mg and am currently on 4mg with my little SWAG with WASP Nano. I will never light up again and am proof that vaping can get a 60 cigs a day smoker to quit tobacco from the get go.

  8. Jacob says:

    Hi, ive just recently started vaping and have been a little worried about wether or not vaping is harmful or not and limiting myself, but the only positive articles i have found is on sites dedicated to vaping so reading this helps put me at ease

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